A Case of IMP-4-, OXA-421-, OXA-96-, and CARB-2-Producing Acinetobacter pittii Sequence Type 119 in Australia

作者：Kamolvit Witchuda; Derrington Petra; Paterson David L; Sidjabat Hanna E^*

来源：Journal of Clinical Microbiology, 2015, 53(2): 727-730.

DOI：10.1128/JCM.02726-14

An IMP-4-producing Acinetobacter pittii strain coproducing oxacillinases was isolated from a leg wound of a 67-year-old female patient. Identification to the species level by rpoB and gyrB sequencing and multiplex-PCR-based analysis revealed that the isolate was A. pittii. Whole-genome sequencing of this A. pittii isolate determined the presence of bla(OXA-96), bla(CARB-2), and a novel bla(OXA-421) gene. The position of this novel bla(OXA-421) gene was similar to that of bla(OXA-51) in A. baumannii, downstream of the phosphinothricin N-acetyltransferase gene and upstream of fxsA in the chromosome. This A. pittii isolate was found to belong to sequence type 119 (ST119). Here, we report the first isolation of IMP-4-producing A. pittii ST119 with a novel bla(OXA-421) gene from a patient in Australia and characterize its draft genome.

• 出版日期2015-2