Dapsone Hypersensitivity Syndrome That Occurred during Treatment of Pediatric Patient with Erythema Elevatum Diutinum

作者：Kim Gun Wook; Park Hyun Je; Kim Hoon Soo; Kim Su Han; Ko Hyun Chang; Kim Byung Soo; Kim Moon Bum^*

来源：Annals of Dermatology, 2011, 23: S290-S295.

DOI：10.5021/ad.2011.23.S3.S290

• Dapsone
• Drug hypersensitivity syndrome
• Erythema elevatum diutinum

Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the emergency clinic because of high fever, emesis, diarrhea, upper respiratory symptoms, and worsening of exanthematous eruptions. A diagnosis of DHS was made, and it improved with oral prednisone. We recommend that pediatric patients who are treated with dapsone need to be observed carefully for the development of DHS. (Ann Dermatol 23(S3) S290 similar to S295, 2011)

• 出版日期2011-12