An X-ray Spectromicroscopy Study of Protein Adsorption to Polystyrene-Poly(ethylene oxide) Blends

作者：Leung Bonnie O; Hitchcock Adam P^*; Brash John L; Scholl Andreas; Doran Andrew

来源：Langmuir, 2010, 26(18): 14759-14765.

DOI：10.1021/la102432g

Synchrotron-based X-ray photoemission electron microscopy (X-PEEM) and atomic force microscopy (A FM) were used to characterize the composition and surface morphology of thin films of a polystyrene-poly(ethylene oxide) blend (PS-PEO), spun cast from dichloromethane at various mass ratios and polymer concentrations X-PEEM reveals incomplete segregation with similar to 30% of PS in the PEO region and vice versa Protein (human scrum albumin) adsorption studies show that this partial phase separation leads to greater protein repellency in the PS region, whereas more protein is detected in the PEO region compared to control samples

• 出版日期2010-9-21