A clinical study of acute pulmonary embolism in internal medicine patients and postoperative patients

作者:Zhang, Jinghua; Yang, Fan; Liu, Jia; Yan, Zhenfu; Zhao, Luosha*
来源:International Journal of Clinical and Experimental Medicine, 2016, 9(5): 7976-7985.

摘要

The aim of this study is to analyze the clinical characteristics of internal medicine and postoperative patients with acute pulmonary embolism (PE) in our hospital. 313 patients with acute PE were selected. Based on whether acute PE had developed postoperatively and whether other concurrent risk factors for PE were present, patients were divided into 4 groups. The oxygen partial pressure was significantly higher and the brain natriuretic peptide (BNP) level was significantly lower in group of postoperative PE patients without other concurrent risk factors compared with other 3 groups. The percentage of postoperative PE patients with other concurrent risk factors who underwent anticoagulant therapy was considerably lower than those 3 groups. There was a positive correlation between diabetes and hemorrhagic complications in internal medicine patients with PE. For all patients, deaths were positively correlated with both increased BNP levels and hypotension. In patients with postoperative PE, deaths were positively correlated with tumor and the decrease of oxygen partial pressure. In conclusion, Patients with postoperative acute PE who had no other concurrent risk factors exhibited a high cardiopulmonary compensatory capacity. For patients with postoperative acute PE who had other concurrent risk factors, the anticoagulant treatments administered by the clinicians were often inadequate. In internal medicine patients with PE, the incidence of hemorrhagic complications was related to diabetes. An elevated BNP level and hypotension increased the risk of death in patients with acute PE. Tumor and hypoxemia increased the risk of death in patients with postoperative acute PE.