An efficient protocol for the eliminative deoxygenation of aliphatic and aromatic epoxides to olefins with polyphosphoric acid as a promoter

作者：Pathe Gulab Khushalrao; Ahmed Naseem^*

来源：Tetrahedron Letters, 2015, 56(45): 6202-6206.

DOI：10.1016/j.tetlet.2015.09.083

• Deoxygenative reaction
• Aliphatic and aromatic epoxides
• Polyphosphoric acid

An efficient eliminative deoxygenation reaction is reported for the conversion of aliphatic and aromatic epoxides to olefins. Polyphosphoric acid (PPA) is used in 30 mol % as a promoter to afford the products in excellent yield (85-96%) at 50 degrees C under neat condition. Our method has advantages such as inexpensive reagents, high yield, stereoselective product in short reaction time under eco-friendly reaction conditions.

• 出版日期2015-11-4