A plasmonic biosensor array by block copolymer lithography

作者:Shin Dong Ok; Jeong Jong Ryul; Han Tae Hee; Koo Chong Min; Park Hye Jeong; Lim Yong Taik*; Kim Sang Ouk
来源:Journal of Materials Chemistry, 2010, 20(34): 7241-7247.
DOI:10.1039/c0jm01319f

摘要

Highly uniform and dense, hexagonal noble metal nanoparticle arrays were achieved on large-area transparent glass substrates via scalable, parallel processing of block copolymer lithography. Exploring their localized surface plasmon resonance (LSPR) characteristics revealed that the Ag nanoparticle array displayed a UV-vis absorbance spectrum sufficiently narrow and intense for biosensing application. A highly-sensitive, label-free detection of prostate cancer specific antibody (anti-PSA) with sub-ng ml(-1) level detection limit (0.1 similar to 1 ng ml(-1)) has been accomplished with the plasmonic nanostructure. Our approach offers a valuable route to a low-cost, manufacture-scale production of plasmonic nanostructures, potentially useful for various photonic and optoelectronic devices.

  • 出版日期2010