Promising near-infrared non-targeted probes: benzothiazole heptamethine cyanine dyes

作者：Okoh Okoh Adeyi; Bi**y Roger H; Lawrence Clare L; Rolph Carole E; Smith Robert B^*

来源：Journal of Sulfur Chemistry, 2014, 35(1): 42-56.

DOI：10.1080/17415993.2013.778258

• benzothiazole
• cyanine dyes
• fluorescence
• growth inhibition
• near infrared

A series of benzothiazole heptamethine cyanine dyes have been synthesized and their photophysical properties evaluated in relation to their structural features. These have been compared against two classical probes of this type: Indocyanine Green (IGC) and New Indocyanine Green (IR-820). Growth inhibitory studies were also performed using a eukaryotic, unicellular organism, fission yeast Schizosaccharomyces pombe. Herein we highlight some potentially interesting candidates with improved fluorescence quantum yields when compared with ICG and IR-820.

• 出版日期2014-1-2