Asymmetric Cyclopropanation Reactions

作者：Bartoli Giuseppe; Bencivenni Giorgio; Dalpozzo Renato^*

来源：Synthesis (Germany), 2014, 46(8): 979-1029.

DOI：10.1055/s-0033-1340838

• cyclization
• asymmetric synthesis
• metal catalysis
• enantioselectivity
• carbenoids

Both physical and organic chemists are interested in the cyclopropane ring, the former owing to the strain inherent to the small ring structure, the latter prompted by the importance of this ring in naturally occurring compounds. In recent years, the increasing interest in enantioselective organic synthesis has led to a large number of papers on the preparation of cyclopropane compounds in enantioenriched form. The last review on asymmetric cyclopropanation reactions is dated 2008, thus an update is necessary with critical comparison of preparations using chiral auxiliaries, chiral metal complexes and organocatalysts. The aim of this review is an overview of these topics from 2008 to mid-2013.

• 出版日期2014-4