A Case of Possible Chagas Transmission by Blood Transfusion in Switzerland

作者：Ries Judith^*; Komarek Adriana; Gottschalk Jochen; Brand Birgit; Amsler Lorenz; Jutzi Markus; Frey Beat M

来源：Transfusion Medicine and Hemotherapy, 2016, 43(6): 415-417.

DOI：10.1159/000446264

• Donor screening
• Transfusion-associated infections
• Chagas disease
• Trypanozoma cruzi

Background: Transfusion-transmitted Chagas disease has been reported from endemic countries in Latin America. Switzerland is a non-endemic country but high prevalence of antibodies against Trypanosoma cruzi was found among immigrants. Immigrants may participate in blood donation; therefore, risk-adapted anti-T. cruzi screening for blood donors was implemented in Switzerland in 2013. Methods: Between January 2013 and July 2015, 1 out of 1,183 at-risk donors, tested at Blood Transfusion Service Zurich, was found anti-T. cruzi IgG-positive. Results and Conclusion: Out of 54 donations given by the index donor (ID), we identified 77 blood products which were delivered to hospitals. Archived serum samples from the donations given during the prior 5 years were available for retrospective testing. All samples from ID revealed positive findings for anti-T. cruzi IgG. Donor-triggered look-back procedure identified a 70-year-old male recipient of a platelet concentrate (PC) donated by ID. The recipient succumbed of acute T. cruzi infection 2 years after transfusion of the PC.

• 出版日期2016