A Drug-Drug Interaction Crystallizes a New Entry Point into the UPR

作者：Shokat Kevan M^*

来源：Molecular Cell, 2010, 38(2): 161-163.

DOI：10.1016/j.molcel.2010.04.011

In the current issue of Molecular Cell, Sicheri and Ron (Wiseman et al. 2010) identify a small molecule, the flavonol quercetin, as an activator of yeast IRE1, a key regulator of the endoplasmic reticulum (ER) unfolded protein response pathway (UPR).

• 出版日期2010-4-23