A Multiligand Based Pd Catalyst for C-N Cross-Coupling Reactions

作者:Fors Brett P; Buchwald Stephen L*
来源:Journal of the American Chemical Society, 2010, 132(45): 15914-15917.
DOI:10.1021/ja108074t

摘要

An alternative approach to catalyst development, which led to a Pd catalyst based on two biarylphosphine ligands for C-N cross-coupling reactions, is reported. By effectively being able to take the form of multiple catalysts this system manifests the best properties that catalysts based on either of the two ligands exhibit separately and displays the highest reactivity and substrate scope of any system that has been reported to date for these reactions.

  • 出版日期2010-11-17