Acid-Catalyzed [3,3] Sigmatropic Rearrangement of N-Cbz-Diaryl Hydrazide for the Synthesis of Mono-N-Cbz-1,1 '-biaryl-2,2 '-diamine

作者：Suh Sung Eun; Park In Keol; Lim Byeong Yun; Cho Cheon Gyu^*

来源：European Journal of Organic Chemistry, 2011, (3): 455-457.

DOI：10.1002/ejoc.201001461

• Sigmatropic rearrangement
• Hydrazides
• Cross-coupling
• Biaryls
• Amines

N-Cbz-Diaryl hydrazides undergo acid-catalyzed [3,3] sigmatropic rearrangement to afford N-Cbz-1,1'-biaryl-2,2'-diamines. The resultant products can be versatile synthetic platforms for a wide variety of C-2- and/or nonsymmetric axially chiral ligands and organocatalysts.

• 出版日期2011-1