Nardoaristolones A and B, Two Terpenoids with Unusual Skeletons from Nardostachys chinensis Batal

作者:Liu, Ming-Li; Duan, Ying-Hui; Hou, Yun-Long; Li, Chang; Gao, Hao; Dai, Yi*; Yao, Xin-Sheng
来源:Organic Letters, 2013, 15(5): 1000-1003.
DOI:10.1021/ol3034466

摘要

Nardoaristolones A and B, two novel terpenoids derived from the aristolane-type sesquiterpenoid, were isolated from the underground parts of Nardostachys chinensis Batal. Nardoaristolone A is the first reported aristolane-chalcone derivative, while nardoaristolone B possesses a nor-aristolane sesquiterpenoid skeleton with an unusual 3/5/6 tricyclic ring system. Their structures were elucidated by spectroscopic measurements, and the absolute configurations were established by single-crystal X-ray diffraction experiments.