An Efficient Synthesis of Benzyl Dithiocarbamates by Base-Promoted Cross-Coupling Reactions of Benzyl Chlorides with Tetraalkylthiuram Disulfides at Room Temperature

作者：Wu, Zhiyong^*; Lai, Miao; Zhang, Siyuan; Zhong, Xianyun; Song, Hao; Zhao, Mingqin^*

来源：European Journal of Organic Chemistry, 2018, 2018(48): 7033-7036.

DOI：10.1002/ejoc.201801449

• Cross-coupling
• Synthetic methods
• Functional dithiocarbamates
• Reaction mechanisms

A straightforward, mild and efficient protocol for the synthesis of benzyl dithiocarbamates from benzyl chlorides and tetraalkylthiuram disulfides is presented. This protocol is compatible with a wide variety of electron-donating and -withdrawing substituents and enables construction of various dithiocarbamate derivatives from readily available starting materials.

• 出版日期2018-12-31
• 单位河南农业大学