Multi-responsive methylcellulose/Fe-alginate-g-PVA/PVA/Fe3O4 microgels for immobilizing enzyme

作者：Xiao Congming^*; Ma Peipei; Geng Nannan

来源：Polymers for Advanced Technologies, 2011, 22(12): 2649-2652.

DOI：10.1002/pat.1701

• triple-responsive
• methylcellulose
• alginate
• PVA
• microgels

To take advantage of the respective character of methylcellulose (MC), poly(vinyl alcohol) (PVA), and alginate, novel physically cross-linked methylcellulose/Fe-alginate-g-PVA/PVA (MC/Fe-Alg-g-PVA/PVA) microgels were prepared by emulsification/thermal gelation/freezing-thawing/ionic cross-linking technique. Subsequently, some ferrous ions bound in the microgels were transformed into magnetite via in situ self oxidation. A model enzyme alpha-amylase was immobilized into microgels by direct adsorption. The release behavior of alpha-amylase indicated that the obtained complex microgels were magnetic-, temperature-, and pH-triple sensitive.

• 出版日期2011-12
• 单位华侨大学