A retrospective comparison of efficacy and safety of 680 consecutive lasik treatments for high myopia performed with two generations of flying-spot excimer lasers

作者：Gazieva Lola^*; Beer Mette Hjuler; Nielsen Kim; Hjortdal Jesper

来源：Acta Ophthalmologica, 2011, 89(8): 729-733.

DOI：10.1111/j.1755-3768.2009.01830.x

• Excimer
• high myopia
• LASIK
• MEL-70
• MEL-80

Purpose: To compare the visual refractive outcome and complication of laser in situ keratomileusis (LASIK) carried out with a Carl Zeiss-Meditec MEL-70 Excimer laser and a MEL-80 laser for treatment of high myopia.
Methods: Journal records of 680 consecutive eyes that underwent LASIK with a Schwind Supratome microkeratome and a MEL-70 Excimer laser (Group A), or a Moria M2 microkeratome and a MEL-80 Excimer laser (Group B) were reviewed. Manifest refraction, uncorrected and best spectacle-corrected visual acuity (BSCVA), corneal topography and central corneal thickness (CCT) were recorded before and 3 months after treatment. Pre- and postoperative complications, visual and refractive outcome and frequency of retreatments were registered.
Results: Mean preoperative spherical equivalent refraction was -8.52 dioptres (-5.50--18 dioptres), and the mean attempted laser correction was -8.02 dioptres (-5.50--11 dioptres). Three months after LASIK, the average treatment error (difference between achieved and attempted correction) was 1.20 (SD = 1.19) dioptres of under correction in Group A and 0.52 (SD = 1.00) dioptres in Group B. Four eyes lost more than two lines of BSCVA (0.6%). In 110 eyes (16%), a re-LASIK procedure was performed to reduce remaining myopia after the primary procedure.
Conclusions: Laser in situ keratomileusis treatment for high myopia can effectively reduce high degrees of myopia. Under correction was observed in both treatment groups but Group B has a slightly better predictability. Significant loss of BSCVA occurs infrequently after LASIK for even considerable grades of myopia (0.6% in each group).

• 出版日期2011-12