DEPIVIH 2: Use of three HIV testing methods in French primary care settings - ELISA laboratory screening versus two rapid point-of-care HIV tests

作者：Papadima D^*; Gauthier R; du Clary F Prevoteau; Bouee S; Conort G; Livrozet J M; Taulera O; Waj**rot A; Majerholc C; Peter J M; Aubert J P

来源：Medecine et Maladies Infectieuses, 2018, 48(2): 122-129.

DOI：10.1016/j.medmal.2017.11.005

• Screening
• HIV RDT
• HIV infection

Objective. - The primary endpoint was to evaluate the use of HIV testing methods by French primary care providers: Elisa laboratory screening, instant result HIV diagnostic test and rapid result HIV diagnostic test. The secondary endpoints were the population screening rate of unknown HIV status consulting during the study period, reasons for screening and for choosing the specific screening method, the investigators' satisfaction with the rapid diagnostic test (RDT) and problems encountered.& para;& para;Patients and methods. - National prospective interventional study with French family physicians (FP) from December 2013 to December 2014. FPs enrolled all consenting adults consulting for an HIV screening test during a 6-month period: the choice was an Elisa laboratory test or one of the two RDTs.& para;& para;Results. - During the study period, 43 FPs included 981 patients. HIV screening was performed for the first time for 31.6% of patients; 767 (78.2%) Elisa laboratory test prescriptions and 214 (21.8%) RDTs were performed, leading to a screening rate of 1.3%. For 120 (15.7%) of the Elisa laboratory tests, the result was not reported and six RDTs were not valid. Nine patients were diagnosed as HIV-infected (0.9%): five with Elisa laboratory test and four with RDT. Almost 90% of FPs were willing to keep on using RDTs in their daily practice.& para;& para;Conclusion. - In general practice, RDTs may be an important additional tool to traditional HIV screening. They could account for one in five tests prescribed in this context.

• 出版日期2018-3