A Clean and Efficient Method for the Synthesis of 3-Aroyl-2,4,6-triaryl-4-hydroxy-1,1-cyclohexanedicarbonitriles in Water

作者：Wang Ai Qing^*; Jin Tong Shou; Liu Li Bin; Cheng Zhao Li; Li Tong Shuang

来源：Asian Journal of Chemistry, 2010, 22(3): 1977-1981.

• 3-Aroyl-2,4,6-triaryl-4-hydroxy-1,1-cyclohexanedicarbonitriles
• Malononitrile
• 1,3-Diaryl-2-propene-1-ones
• Clean synthesis

A clean and efficient chemistry route to the synthesis of 3-aroyl-2,4,6-triaryl-4-hydroxy-1,1-cyclohexanedicarbonitriles using hexadecyltrimethyl ammonium bromide (HTMAB) as the catalyst (5 mol%) in aqueous media is described. This method provides several advantages Such as neutral conditions, high yields and simple work-up procedure. In addition. water was chosen as a green solvent.

• 出版日期2010-3
• 单位河北大学