A novel approach to investigate neuronal network activity patterns affected by deep brain stimulation in rats

作者:Klein Julia; Soto Montenegro Maria L; Pascau Javier; Guenther Lydia; Kupsch Andreas; Desco Manuel; Winter Christine*
来源:Journal of Psychiatric Research, 2011, 45(7): 927-930.
DOI:10.1016/j.jpsychires.2010.12.008

摘要

The establishment of new therapeutic indications for deep brain stimulation (DBS) is ambitiously promoted though the underlying mechanisms remain contested. Here, we report that PET-imaging and subsequent c-Fos-immunostaining in rats constitute a new translational approach to further understand DBS-mechanisms and -effectiveness.

  • 出版日期2011-7