Dynamic Imaging of functionalized multi-walled carbon nanotube systemic circulation and urinary excretion

作者：Lacerda Lara; Soundararajan Anuradha; Singh Ravi; Pastorin Giorgia; Al Jamal Khtdoud T; Turton John; Frederik Peter; Herrero Maria A; Bao Shouping Li Ande; Emfietzoglou Dimitris; Mather Stephen; Phillips William T; Prato Maurizio; Bianco Alberto; Goins Beth; Kostarelos Kostas^*

来源：Advanced Materials, 2008, 20(2): 225-+.

DOI：10.1002/adma.200702334

Intravenously administered multi-walled carbon nanotubes, functionalized with DTPA and radiolabeled with Indium-111, were dynamically tracked in vivo using a microSingle Photon Emission Tomography scanner. Imaging showed that nanotubes enter the systemic blood circulation and within 5 min begin to permeate through the renal glomerular filtration system into the bladder.

• 出版日期2008-1-18