Unimolecular 4-Hydroxypiperidines: New Ligands for Copper-Catalyzed N-Arylation

作者:Patil Pradnya H; Nallasivam Jothi L; Fernandes Rodney A*
来源:Asian Journal of Organic Chemistry, 2015, 4(6): 552-559.
DOI:10.1002/ajoc.201500062

摘要

A family of 4-hydroxypiperidines based mono, bis, tris, and tetrakis unimolecular compounds served as efficient ligands in combination with inexpensive CuI to catalyze Ullmann coupling reactions. A wide range of N-arylated indoles, benzimidazoles, imidazoles, pyrroles, and adenines were synthesized in moderate to excellent yields.

  • 出版日期2015-6