Association Between Platelet Count and Components of Metabolic Syndrome in Geriatric Taiwanese Women

作者：Chen Yen Lin; Hsu Chun Hsien; Hseih Chang Hsung; Wang Kun; Wu Chung Ze; Wang Cheng Yi; Wang Jen Yu; Chang Jin Biou; Pei Dee^*

来源：International Journal of Gerontology, 2012, 6(3): 201-205.

DOI：10.1016/j.ijge.2012.01.015

• body mass index
• low-density lipoprotein-cholesterol
• metabolic syndrome
• platelet count
• triglyceride

Background: The growing elderly population in Taiwan, as in many other countries, has resulted in increased importance of the metabolic syndrome (MetS). Although it has been reported in different age groups, the relationship between platelets and MetS remains unknown in geriatric patients. %26lt;br%26gt;Patients and Methods: We enrolled 1460 women %26gt;65 years old. Women with a known history of diabetes, hyperlipidemia or hypertension or those taking medication for these conditions were all excluded. The women were further divided into quartiles arbitrarily according to platelet count (PC) (PC1-PC4, lowest to highest accordingly). %26lt;br%26gt;Results: Among the MetS components, body mass index (BMI), total cholesterol, low-density lipoprotein cholesterol (LDL-C) and log transformation triglyceride (Log TG) were all significantly higher in the PC4 group (p %26lt; 0.05), and they were also positively correlated with PC. However, in multiple regression, BMI became nonsignificant. Both LDL-C and Log TG were the only two factors that remained positively and independently correlated with PC. Compared to PC1, all the other three groups had significantly higher odds ratios for having MetS (2.013, 1.473-2.751; 1.486, 1.081-2.042; 1.537, 1.117-2.114; odds ratios and 95% confidence intervals for PC4, PC3 and PC2, respectively). %26lt;br%26gt;Conclusion: Elderly women with MetS had higher PC. Among the five components, TG was positively correlated with PC. There was a positive correlation between PC and LDL-C but not high-density lipoprotein cholesterol. The importance of both lipids might be re-evaluated in the future in older women.

• 出版日期2012-9