A single-step, mild, neutral, catalyst-free method for cyanohydrin synthesis

作者:Degani Mariam S*; Kakwani Manoj D; Desai Nutan H Palsule; Bairwa Ranjeet
来源:Monatshefte fur Chemie, 2012, 143(3): 461-465.
DOI:10.1007/s00706-011-0613-4

摘要

A wide variety of carbonyl compounds can be transformed to their corresponding cyanohydrins in a single step using a dimethyl sulfoxide (DMSO)-water system in excellent yields (75-94%). The major advantages of this system are that the reaction conditions are mild and neutral; the reaction proceeds without catalyst and gives the corresponding cyanohydrins in short time (15-120 min).

  • 出版日期2012-3

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