An Adenine Code for DNA: A Second Life for N6-Methyladenine

作者:Heyn Holger; Esteller Manel*
来源:Cell, 2015, 161(4): 710-713.
DOI:10.1016/j.cell.2015.04.021

摘要

DNA N6-methyladenine (6mA) protects against restriction enzymes in bacteria. However, isolated reports have suggested additional activities and its presence in other organisms, such as unicellular eukaryotes. New data now find that 6mA may have a gene regulatory function in green alga, worm, and fly, suggesting m6A as a potential "epigenetic'' mark.

  • 出版日期2015-5-7