Micromanaging the Classification of Colon Cancer: The Role of the microRNAome

作者:Vilar Eduardo*; Tabernero Josep; Gruber Stephen B
来源:Clinical Cancer Research, 2011, 17(23): 7207-7209.
DOI:10.1158/1078-0432.CCR-11-2440

摘要

Recent advances in our understanding of the microRNAome (miRNAome) have provided further insights into the molecular pathogenesis of colorectal cancer and shown a potential role for miRNAs in distinguishing molecular subtypes. The mucosa-adenoma-carcinoma model can now integrate miRNAs into the known genetic alterations that drive the progression of colorectal neoplasia. Clin Cancer Res; 17(23); 7207-9.

  • 出版日期2011-12-1