Assessing breast tumor margin by multispectral photoacoustic tomography

作者:Li Rui*; Wang Pu; Lan Lu; Lloyd Frank P Jr; Goergen Craig J; Chen Shaoxiong; Cheng Ji Xin
来源:Biomedical Optics Express, 2015, 6(4): 1273-1281.
DOI:10.1364/BOE.6.001273

摘要

An unmet need exists in high-speed and highly-sensitive intraoperative assessment of breast cancer margin during conservation surgical procedures. Here, we demonstrate a multispectral photoacoustic tomography system for breast tumor margin assessment using fat and hemoglobin as contrasts. This system provides similar to 3 mm tissue depth and similar to 125 mu m axial resolution. The results agreed with the histological findings. A high sensitivity in margin assessment was accomplished, which opens a compelling way to intraoperative margin assessment.

  • 出版日期2015-4-1