Analysis on the risk factors of medication-overuse headache in Chinese patients

作者：Li, Junxia; Chen, Chunfu^*; Zhang, Ligong; Cui, Xiaochen; Wei, Chuanqiao; Diao, Xiaojun

来源：Journal of Clinical Neuroscience, 2018, 48: 153-159.

DOI：10.1016/j.jocn.2017.10.066

• Chronic migraine
• Medication-overuse headache
• Risk factors
• Unconditional logistic analysis

Objective: The purpose of this study was to analyze the risk factors of medication-overuse headache in patients with chronic migraine in China.
Materials and methods: 157 patients who were diagnosed as chronic migraine were chosen from headache outpatients of Shandong Provincial Hospital affiliated to Shandong University. Based on a standardized questionnaire, a database was developed and analyzed with 45 indexes.
Results: The independent risk factors of medication-overuse headache identified in this study included the frequency of medicine overuse (OR = 9.575, 95%CI, 3.573-35.659), Allodynia Symptom Checklist scores (OR = 5.846, 95%CI, 2.065-22.856), anxiety disorder (OR = 2.902, 95%CI, 1.601-7.476) and lack or non-standardized preventive treatment (OR = 1.173, 95%CI, 1.073-3.826).
Conclusions: The frequency of medicine overuse, Allodynia Symptom Checklist scores, anxiety disorder and lack or non-standardized preventive therapy were the independent risk factors for medication overuse headache in patients with chronic migraine.

• 出版日期2018-2
• 单位山东省立医院; 山东大学; 聊城市人民医院; 山东第一医科大学