A severely immunocompromised child with uncomplicated oseltamivir-resistant 2009 H1N1 pandemic influenza infection

作者:Hyle Emily P*; Shu Bo; Lindstrom Stephen; Klimov Alexander; Hancock Kathy; Ferraro Mary J; Traum Avram Z; Michelow Ian C
来源:Pediatric Transplantation, 2012, 16(5): E158-E161.
DOI:10.1111/j.1399-3046.2011.01490.x

摘要

Hyle EP, Shu B, Lindstrom S, Klimov A, Hancock K, Ferraro MJ, Traum AZ, Michelow IC. A severely immunocompromised child with uncomplicated oseltamivir-resistant 2009 H1N1 pandemic influenza infection. Abstract: 2009 H1N1 pandemic influenza was associated with increased risk for severe disease in children and the immunosuppressed. We report a case of uncomplicated pneumonia because of infection with oseltamivir-resistant 2009 H1N1 virus in an immunosuppressed pediatric renal transplant patient. Innate immunity and/or altered viral fitness may be responsible for the mild clinical phenotype of the case.

  • 出版日期2012-8