Allergen immunotherapy for allergic asthma: protocol for a systematic review

作者:Dhami Sangeeta*; Nurmatov Ulugbek; Agache Ioana; Lau Susanne; Muraro Antonella; Jutel Marek; Roberts Graham; Akdis Cezmi; Bonini Matteo; Calderon Moises; Casale Thomas; Cavkaytar Ozlem; Cox Linda; Demoly Pascal; Flood Breda; Hamelmann Eckard; Izuhara Kenji; Kalayci Omer; Kleine Tebbe Jorg; Nieto Antonio; Papadopoulos Nikolaos; Pfaar Oliver; Rosenwasser Lanny; Ryan Dermot; Schmidt Weber Carsten; Szefler Stan; Wahn Ulrich; van Wijk Roy Gerth; Wilkinson Jamie
来源:Clinical and Translational Allergy, 2016, 6(1): 5.
DOI:10.1186/s13601-016-0094-y

摘要

Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for Allergic Asthma. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of allergic asthma. Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.