Vitamin D in Atopic Dermatitis, Asthma and Allergic Diseases

作者：Searing Daniel A; Leung Donald Y M^*

来源：Immunology and Allergy Clinics of North America, 2010, 30(3): 397-+.

DOI：10.1016/j.iac.2010.05.005

• Vitamin D
• Atopic dermatitis
• Asthma
• Allergy

This review examines the scientific evidence behind the hypothesis that vitamin D plays a role in the pathogenesis of allergic diseases, along with a focus on emerging data regarding vitamin D and atopic dermatitis. Elucidated molecular interactions of vitamin D with components of the immune system and clinical data regarding vitamin D deficiency and atopic diseases are discussed. The rationale behind the sunshine hypothesis, laboratory evidence supporting links between vitamin D deficiency and allergic diseases, the clinical evidence for and against vitamin D playing a role in allergic diseases, and the emerging evidence regarding the potential use of vitamin D to augment the innate immune response in atopic dermatitis are reviewed.

• 出版日期2010-8