Note on the Measurement of Bulk Density and Tapped Density of Powders According to the European Pharmacopeia

作者：Sousa e Silva J P; Splendor D; Goncalves I M B; Costa P; Sousa Lobo J M

来源：AAPS PHARMSCITECH, 2013, 14(3): 1098-1100.

DOI：10.1208/s12249-013-9994-5

• bulk density
• compressibility index
• excipients
• tapped density

The apparent volume and compressibility index of commonly used excipients were evaluated according to European Pharmacopeia monograph (seventh edition) in order to study the influence of the procedure conditions. The results suggested that the leveling of the powder inside the cylinder ought to be avoided.

• 出版日期2013-9