Anti Pseudorabies Virus Activity of Kumazasa Extract

作者：Iwata Kei; Naito Erika; Yamashita Kazutaka; Kakino Kenichi; Taharaguchi Satoshi^*; Kimachi Yoshihisa; Hara Motonobu; Takase Kozo

来源：Biocontrol Science, 2010, 15(4): 123-128.

DOI：10.4265/bio.15.123

• Antiviral activity
• Kumazasa
• Medicinal plant
• Pseudorabies virus
• Polysaccharide

Sasa veitchii or "kumazasa" has been used for the preservation of food, or preventing bacterial activity. However, the antiviral activity of kumazasa is poorly understood. In the present study, the antiviral activity of kumazasa extract (KE) was assessed by the plaque reduction assay for the pseudorabies virus (PRV). KE reduced 99% of the plaque formation of PRV at concentrations of 1.2%, showing that KE inhibited PRV adsorption to cells and 1E180 expression. The polysaccharide fraction of KE showed a concentration dependent inhibition of PRV plaque formation. We conclude that KE possesses potent anti PRV activity, and the candidate responsible for the antiviral property was the polysaccharide fraction.

• 出版日期2010-12