科研之友
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摘要
The 1,3-dipolar cycloaddition reaction of azomethine ylides generated in situ from isatin and sarcosine with 5-arylmethylene-3-phenyl-2-thioxothiazolidin-4-one in refluxing toluene produced the 2''-thioxodispiro[indole-3,2'-pyrrolidine-3',5''-[1,3]thiazolidine]-2,4''-dione derivatives in good yields (80-88%). The structures were assigned by H-1 NMR, IR, elementary analysis and single crystal X-ray diffraction analysis through which the cycloaddition reaction was found to be highly regio- and stereo-selective.
- 出版日期2015-3
- 单位河北科技大学
