A novel in situ deposition of hydroxyapatite nanoplates using anodization/hydrothermal process onto magnesium alloy surface towards third generation biomaterials

作者：Mousa Hamouda M; Tiwari Arjun Prasad; Kim Jinwoo; Adhikari Surya Prasad; Park Chan Hee^*; Kim Cheol Sang

来源：Materials Letters, 2016, 164: 144-147.

DOI：10.1016/j.matlet.2015.10.145

• Magnesium alloy
• Biomaterials
• Hydrothermal deposition
• Bone tissue regeneration
• Biomimetic

Third-generation biomaterials aim to stimulate specific cellular responses at the molecular level, these materials characterized with a resorbable and bioactivity that help body heal once they have been implanted. Here, a biomimetic method was used to generate hydroxyapatite (HA) nanoplates on the surface of AZ31B Mg alloy via anodization in simulated body fluid (SBF), followed by a hydrothermal (HT) process. The resulting nanoplates were characterized using FE-SEM, XRD, and FT-IR, surface hydrophobicity, in addition, corrosion was assessed electrochemically. The excellent bioactivity of the treated samples compared with naked ones were confirmed in vitro with MC3T3-E1 osteoblastic cells with significant growth and proliferation.

• 出版日期2016-2-1