A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

作者:Chen Xiaoqiang; Lee Kyung Ah; Ha Eun Mi; Lee Kyung Mi; Seo You Yeong; Choi Han Kyoung; Kim Ha Na; Kim Min Jung; Cho Chun Seok; Lee Soo Young; Lee Won Jae*; Yoon Juyoung
来源:Chemical communications, 2011, 47(15): 4373-4375.
DOI:10.1039/c1cc10589b

摘要

A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

  • 出版日期2011