A convergent synthesis of vinyloxyimidazopyridine via Cu(I)-catalyzed three-component coupling

作者:Samanta Sadhanendu; Mondal Susmita; Hajra Alakananda
来源:Organic and Biomolecular Chemistry, 2018, 16(7): 1088-1092.
DOI:10.1039/c7ob02883k

摘要

The synthesis of vinyloxyimidazopyridine with complete regio- and stereoselectivity has been achieved by the Cu(i)-catalyzed three-component coupling of 2-aminopyridine, 2-oxoaldehyde and alkyne. This protocol is operationally simple and has much potential for the synthesis of heteroarylated vinyl ethers.

  • 出版日期2018-2-21