A water-soluble perylene dye functionalised with a 17 beta-estradiol: a new fluorescent tool for steroid hormones

作者:Cespedes Guirao Francisco J; Ropero Ana B; Font Sanchis Enrique; Nadal Angel*; Fernandez Lazaro Fernando; Sastre Santos Angela
来源:Chemical communications, 2011, 47(29): 8307-8309.
DOI:10.1039/c1cc10966a

摘要

We have successfully been able to synthesise a specific estrogen receptor-directed biolabel based on a fluorescent water-soluble perylenebisimide, thus offering great potential for determining the presence of estrogen receptors in any kind of cell. Moreover, this synthetic strategy allows the preparation of other conjugates involved in the study of any kind of receptor, simply by selecting the appropriate agonist or antagonist.

  • 出版日期2011