Macroscopic and microscopic observations of needle insertion into gels

作者：van Veen Youri R J^*; Jahya Alex; Misra Sarthak

来源：Proceedings of the Institution of Mechanical Engineers - Part H: Journal of Engineering in Medicine , 2012, 226(H6): 441-449.

DOI：10.1177/0954411912443207

• Bevel-tip needle
• biopsy
• confocal microscopy
• elasticity
• needle insertion
• needle-tissue interactions
• tissue rupture

Needle insertion into soft tissue is one of the most common medical interventions. This study provides macroscopic and microscopic observations of needle-gel interactions. A gelatin mixture is used as a soft-tissue simulant. For the macroscopic studies, system parameters, such as insertion velocity, needle diameter, gel elasticity, needle tip shape (including bevel angle) and insertion motion profile, are varied, while the maximum insertion force and maximum needle deflection are recorded. The needle tip and gel interactions are observed using confocal microscopic images. Observations indicate that increasing the insertion velocity and needle diameter results in larger insertion forces and smaller needle deflections. Varying the needle bevel angle from 8 degrees to 82 degrees results in the insertion force increasing monotonically, while the needle deflection does not. These variations are due to the coupling between gel rupture and tip compression interactions, which are observed during microscopic studies. Increasing the gel elasticity results in larger insertion forces and needle deflections. Varying the tip shapes demonstrates that bevel-tipped needles produce the largest deflection, but insertion force does not vary among the tested tip shapes. Insertion with different motion profiles are performed. Results show that adding 1 Hz rotational motion during linear insertion decreases the needle deflection. Increasing the rotational motion from 1 Hz to 5 Hz decreases the insertion force, while the needle deflection remains the same. A high-velocity (250 mm/s and 300 mm/s) tapping during insertion yields no significant decrease in needle deflection and a slight increase in insertion force.

• 出版日期2012