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摘要
ObjectiveTo document central corneal thickness (CCT) and power measurements in pigmented and white rabbits using Visante anterior segment optical coherence tomography (AS-OCT) and the Humphrey ATLAS Corneal Topography System (HACTS). @@@ Animal studiedFourteen female rabbits (seven pigmented and seven white rabbits) were involved in this study. @@@ ProcedureTwenty-eight eyes underwent AS-OCT and HACTS examination. Central corneal thickness, corneal power in the steepest and flattest meridians, astigmatism, pupil diameter (PD), and white-to-white (WTW) were calculated. @@@ ResultsThe CCT was 39014.2 and 373 +/- 7.2m for pigmented and white rabbits, respectively. The CCT values showed statistical difference between the two breeds (P=0.017). The corneal power in the steepest meridian was 44.6 +/- 1.9Diopter (D) in pigmented rabbits and 47.8 +/- 1.5D in white rabbits. The corneal power in the flattest meridian was 44.0 +/- 2.1D in pigmented rabbits and 47.4 +/- 1.5D in white rabbits. The astigmatism, PD, and WTW values were 0.6 +/- 0.22D, 7.9 +/- 0.9, and 14.5 +/- 0.1mm in pigmented rabbits, respectively. The corresponding values in white rabbits were 0.4 +/- 0.23D, 7.5 +/- 0.5, and 13.5 +/- 0.2mm. There was a statistically significant difference in corneal power in the steepest and flattest meridians and for WTW. No such difference was observed for astigmatism or PD between them. @@@ ConclusionsDifferences exist in the CCT, corneal power, and WTW between 5-month-old pigmented and white rabbits. Such difference should be considered when designing cornea-related experiments in rabbits.
