Aged ginseng (Panax ginseng Meyer) reduces blood glucose levels and improves lipid metabolism in high fat diet-fed mice

作者：Chung Soo Im; Nam Su Jin; Xu Mingze; Kang Mi Young; Lee Sang Chul^*

来源：Food Science and Biotechnology, 2016, 25(1): 267-273.

DOI：10.1007/s10068-016-0039-1

• aged ginseng
• red
• lipid
• glucose

Aged ginseng is unpeeled ginseng root that has been dried and heat-treated in an oven at 80A degrees C for 14 days. The effects of aged ginseng, in comparison with white and red ginseng, on the lipid and glucose metabolism in high fat-fed mice were investigated. C57BL/6N mice were randomly divided into six dietary groups of normal control, high fat, and high fat supplemented with white, red, aged four-year old, and aged five-year old ginseng. After 8 weeks, ginseng counteracted high fat dietinduced body weight gain, hyperlipidemia, and hyperglycemia via a mechanism involving modulation of hepatic lipogenesis, adipokine production, and glucose-regulating enzyme activities. Aged ginseng showed greater antihyperlipidemic and antihyperglycemic activities than white ginseng and exhibited physiological effects similar to red ginseng, perhaps due to a relatively high ginsenoside content. Aged ginseng can be beneficial as a functional food.

• 出版日期2016-2