科研之友
微信
新浪微博
Facebook
分享链接
摘要
Nitroalkanes underwent fast additions to a variety of structurally diverse alclehydes under the catalysis of D-aminoacylase in DMSO. The influences of reaction conditions including solvents, temperature, enzyme concentration and molar ratio of substrates were systematically investigated. Seventeen products were obtained in short time with moderate to high yields. It is the first report on hydrolase-catalyzed fast Henry reaction in organic solvent.
- 出版日期2010-2-1
- 单位浙江大学
