A New Route for the Synthesis of 1 '-Iodoferrocenecarboxaldehyde

作者：Guo Jian^*; Zhuang Shun; Chen Songhua; Zhang Shibo; Yuan Yaofeng

来源：Chinese Journal of Organic Chemistry, 2009, 29(8): 1264-1266.

• ferrocene derivative
• Vilsmeier formylation
• 1 '-iodoferrocenecarbaidehyde

Ferrocenecarboxaldehyde is an important intermediate in organic synthetic chemistry. The application of 1'-substituted ferrocenecarboxaldehyde is limited because of the difficulty of synthesis. Due to many reactive sites, 1'-iodoferrocenecarboxaldehyde was widely used in the design and synthesis of functional molecules. The traditional synthetic methods not only require four steps, but also need to use expensive metal-organic reagents. 1'-Iodoferrocenecarboxaldehyde has been prepared from ferrocene through an improved three-step procedure, which features ready availability of the starting materials and simple operation.

• 出版日期2009-8
• 单位福州大学