Double axial chirality promoted asymmetric [2,3] Stevens rearrangement of N-cinnamyl L-alanine amide-derived ammonium ylides

作者：Tayama Eiji^*; Naganuma Noriko; Iwamoto Hajime; Hasegawa Eietsu

来源：Chemical Communications, 2014, 50(52): 6860-6862.

DOI：10.1039/c4cc02536a

The base-induced asymmetric [2,3] Stevens rearrangement of N-cinnamyl tetraalkylammonium ylides derived from L-alanine amides proceeds via a double axially chiral intermediate to afford the corresponding alpha-substituted alanine derivatives with high enantio-and diastereoselectivities.

• 出版日期2014