A closer insight into the mechanism operating in the trifluoroacetylation of pyrrole. New trifluoromethyl pyrroylmethane discovered

作者：Pelaez W J; Paci M A Burgos; Arguello G A

来源：Tetrahedron Letters, 2009, 50(17): 1934-1938.

DOI：10.1016/j.tetlet.2009.02.048

A former studied of acetylation of pyrrole was revisited and this allowed the identification of new compounds and the isolation and characterization of a very stable solid (2,2 ',2 ''-(2,2,2-trifluoroe-thane-1,1,1-triyl)tris(1H-pyrrole)). All these materials were probably missed, buried in the black tar that characterized the reaction. A careful and thorough selection of the reaction's conditions provided both evidence for three new compounds and a closer insight into the mechanism operating at room and lower temperatures.

• 出版日期2009-4-29