Endoscopic low-coherence topography measurement for upper airways and hollow samples

作者:Delacretaz Yves*; Shaffer Etienne; Pavillon Nicolas; Kuehn Jonas; Lang Florian; Depeursinge Christian
来源:Journal of Biomedical Optics, 2010, 15(6): 066014.
DOI:10.1117/1.3512218

摘要

To evaluate the severity of airway pathologies, quantitative dimensioning of airways is of utmost importance. Endoscopic vision gives a projective image and thus no true scaling information can be directly deduced from it. In this article, an approach based on an interferometric setup, a low-coherence laser source and a standard rigid endoscope is presented, and applied to hollow samples measurements. More generally, the use of the low-coherence interferometric setup detailed here could be extended to any other endoscopy-related field of interest, e.g., gastroscopy, arthroscopy and other medical or industrial applications where tri-dimensional topology is required. The setup design with a multiple fibers illumination system is presented. Demonstration of the method ability to operate on biological samples is assessed through measurements on ex vivo pig bronchi.

  • 出版日期2010-12