Asymmetric porous membranes formed by coagulation-induced phase separation in poly(ether sulfone)/poly(vinyl pyrrolidone)/genistein blends

作者：Chang Teng; Neelakandan Chandrasekaran; Kyu Thein^*; Tseng Yu Tsan; DeFine Linda; Alexander Thomas

来源：Polymer, 2014, 55(20): 5235-5244.

DOI：10.1016/j.polymer.2014.07.044

• Genistein
• Polymer blends
• Asymmetric membrane

Development of asymmetric channel morphology driven by coagulation-induced phase separation of genistein (G) modified poly(ether sulfone)/poly(vinyl pyrrolidone) (PES/PVP) blends has been examined in relation to their miscibility phase diagram. PES/G pairs turned out to be miscible in the amorphous state, whereas solid-liquid phase separation occurred at high genistein compositions. The solid liquid phase diagram involving the liquidus and solidus lines were computed self-consistently in the framework of the combined free energy of Flory-Huggins for liquid liquid phase separation and phase field free energy for crystal solidification. The ternary phase diagram of PES/PVP/G blends was subsequently established that consisted of various coexistence regions. The actual amounts of genistein incorporated in the PES/PVP membranes were determined as a function of weight percent of genistein in feed. On the basis of UV-vis spectroscopy, the extent of genistein leaching during incubation in human blood was evaluated in conjunction with the PVP leaching from the blend membrane.

• 出版日期2014-9-26