Decreased Susceptibility to Tigecycline Mediated by a Mutation in mlaA in Escherichia coli Strains

作者：He, Fang; Xu, Juan; Wang, Jianfeng; Chen, Qiong; Hua, Xiaoting; Fu, Ying; Yu, Yunsong^*

来源：Antimicrobial Agents and Chemotherapy, 2016, 60(12): 7530-7531.

DOI：10.1128/AAC.01603-16

• RESISTANT KLEBSIELLA-PNEUMONIAE
• RIBOSOMAL S10 PROTEIN
• EFFLUX PUMP
• ACRAB

<jats:p>Tigecycline, a type of glycylcycline, is a novel expanded-spectrum antibiotic that active against most Gram-negative and Gram-positive bacteria, including antibiotic-resistant strains such as carbapenem-resistant Enterobacteriaceae (1-3).…</jats:p>

• 出版日期2016-12
• 单位浙江省医学科学院; 浙江大学; 杭州师范大学; 杭州市第一人民医院