Anthryl-doped conjugated polyelectrolytes as aggregation-based sensors for nonquenching multicationic analytes

作者：Satrijo Andrew; Swager Timothy M^*

来源：Journal of the American Chemical Society, 2007, 129(51): 16020-16028.

DOI：10.1021/ja075573r

The fluorescence-based detection of nonquenching, multicationic small molecules has been demonstrated using a blue-emitting, polyanionic poly(p-phenylene ethynylene) (PPE) doped with green-emitting exciton traps (anthryl units). Multicationic amines (spermine, spermidine, and neomycin) were found to effectively induce the formation of tightly associated aggregates between the polymer chains in solution. This analyte-induced aggregation, which was accompanied by enhanced exciton migration in the PPE, ultimately led to a visually noticeable blue-to-green fluorescence color change in the solution. The aggregation-based sensor exhibited poor sensitivity toward dicationic and monocationic amines, demonstrating that a conjugated polyelectrolyte sensor relying on nonspecific, electrostatic interactions may still attain a certain level of selectivity.

• 出版日期2007-12-26