Antibodies Induced by Dengue Virus Type 1 and 2 Envelope Domain III Recombinant Proteins in Monkeys Neutralize Strains with Different Genotypes

作者：Bernardo Lidice; Fleitas Osmel; Pavon Alequis; Hermida Lisset; Guillen Gerardo; Guzman Maria G^*

来源：Clinical and Vaccine Immunology, 2009, 16(12): 1829-1831.

DOI：10.1128/CVI.00191-09

In the present work, we evaluated the neutralizing capacity of the antibodies induced by dengue virus type 1 and 2 envelope domain III recombinant proteins in monkeys against strains of different dengue virus type 1 and 2 genotypes. Here we demonstrated that dengue virus type 1 and 2 recombinant proteins induced high titers of neutralizing antibodies against different genotype strains.

• 出版日期2009-12