Application of a non-amplification-based technology to detect invasive fungal pathogens

作者：Hsu Joe L^*; Binkley Jon; Clemons Karl V; Stevens David A; Nicolls Mark R; Holodniy Mark

来源：Diagnostic Microbiology and Infectious Disease, 2014, 78(2): 137-140.

DOI：10.1016/j.diagmicrobio.2013.11.013

• Invasive fungal disease
• Diagnosis
• Aspergillus
• Candida
• nCounter analysis system

Current diagnostic techniques for fungal diseases could be improved with respect to sensitivity, specificity, and timeliness. To address this clinical need, we adapted a non-amplification-based nucleic acid detection technology to identify fungal pathogens. We demonstrate a high-specificity, detection sensitivity, reproducibility, and multiplex capacity for detecting fungal strains.

• 出版日期2014-2
• 单位河北医科大学